LINCOLN, Neb. - Taylor Martinez threw for a career-high 354 yards and matched his high with five touchdown passes to lead No. 17 Nebraska to a 49-20 victory over Southern Mississippi on Saturday.
The Huskers won their nation-leading 27th straight opener.
Nebraska played the last three quarters without Rex Burkhead. The 1,300-yard rusher last season went out with a sprained ligament in his left knee after opening the scoring with a career-long 57-yard run.
Backup Ameer Abdullah ran 15 times for 81 yards and made an acrobatic catch for an 11-yard TD.
Southern Miss backup quarterback Anthony Alford carried 15 times for 84 yards in his first college game.
The Golden Eagles, with first-year coach Ellis Johnson, scored their first touchdown on Tracey Lampley's 100-yard kickoff return. They tied it 14-14 on first-time starter Chris Campbell's 24-yard pass to Dominique Sullivan.
Nebraska's go-ahead TD came on Martinez's 9-yard pass to Jake Long.